Surgical Approach and Laser Applications in BRONJ Osteoporotic and Cancer Patients
Table 3
Protocols used for different therapeutical approaches.
Treatment
Protocols
G1
Medical therapy
Antibiotic therapy (oral amoxicillin 1 gr 2 times/day with oral metronidazole 250 mg 2 times/day) for two weeks. Mouthwashes with chlorhexidine (0.20%) and hydrogen peroxide (3%) two/three times a day.
G2
Medical therapy + LLLT
G1 protocol + LLLT applications once a week for two months with Nd:YAG Laser (1.25 W, 15 Hz, VSP, 320 μm) of fibre diameter, nonfocused way with scanning method, 2 mm from tissue, for 1 minute and repeated 5 times.
G3
Traditional surgery
Antibiotic treatment prescribed beginning three days prior to the operation and ending 10 days after it. Conservative surgical treatments using traditional surgical instruments consisted in sequestrectomy of necrotic bone or superficial debridement/curettage or corticotomy/surgical removal of alveolar and/or cortical bone.
G4
Traditional surgery + LLLT
G3 protocol + LLLT applications once a week for two months with Nd:YAG Laser (1.25 W, 15 Hz, VSP, 320 μm) of fibre diameter, nonfocused way with scanning method, 2 mm from tissue, for 1 minute and repeated 5 times.
G5
Er:YAG laser surgery
Antibiotic treatment prescribed beginning three days prior to the operation and ending 10 days after it. Bone resection or vaporization of the necrotic areas was obtained with Er:YAG laser with variable parameters, from 250 mJ 20 Hz (VSP) with a fluence of 50 J/cm² up to 300 mJ, 30 Hz and fluence of 60 J/cm2.
