Normative Data for Bone Mass in Healthy Term Infants from Birth to 1 Year of Age

Table 3

Mean ± SD (𝑛) bone mineral content of whole body, femur, lumbar spine, and bone area, areal bone mineral density, and volumetric bone mineral density of the lumbar spine from birth to 12 mo of age in term infants. Means with different superscript letters indicate statistically significant differences between time points (𝑃<0.05, post-Tukey adjustment).

Site	Term		6 mo		12 mo
Total WB BMC, g	75.98 ± 14.17^a	(52)	169.48 ± 29.01^b	(35)	227.0 ± 29.73^c	(11)
Total WB BMC/body weight, g/kg	20.71 ± 2.49^a	(52)	21.41 ± 1.89^a	(35)	23.39 ± 1.17^b	(11)
WB BMC less head, g	43.58 ± 8.13^a	(52)	87.66 ± 16.32^b	(35)	114.8 ± 21.86^c	(11)
WB BMC less head/body weight, g/kg	11.89 ± 1.59^a	(52)	11.04 ± 1.08^b	(35)	11.75 ± 0.75^a,b	(11)
Femur BMC, g	2.94 ± 0.54^a	(61)	5.58 ± 1.46^b	(60)	8.50 ± 1.84^c	(54)
Lumbar spine BMC, g	2.35 ± 0.42^a	(62)	3.59 ± 0.63^b	(62)	5.37 ± 1.02^c	(57)
Lumbar spine area, cm^2	8.86 ± 1.10^a	(62)	14.28 ± 2.01^b	(62)	17.67 ± 2.52^c	(57)
Lumbar spine areal BMD, g/cm^2	0.266 ± 0.044^a	(62)	0.252 ± 0.031^a	(62)	0.304 ± 0.044^b	(57)
Lumbar spine volumetric BMD, g/cm^3	0.090 ± 0.017^a	(62)	0.067 ± 0.010^b	(62)	0.073 ± 0.012^b	(57)