Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background

Table 1

Index of Microcirculation, coefficient of endothelial dysfunction and the average width of bone trabecular in the proximal metaphysis of the femur, the once received treatment with the studied medication is compared with control group.

Animal group	Level of microcirculation (in PE)	Coefficient of endothelial dysfunction	The average width of bone trabeculae (in 𝜇m)
The intact with fracture	100.5 ± 4.4	1.3 ± 0.2	97.68 ± 1.0
Osteoporosis + fracture	61.5 ± 3.7	2.4 ± 0.2	61.68 ± 1.2
Osteoporosis + fracture + enalapril 0.5 mg/kg	93.3 ± 4.4	1.6 ± 0.1	75.65 ± 0.7
Osteoporosis + fracture + losartan 6 mg/kg	100.0 ± 2.3	1.5 ± 0.2	84.76 ± 0.6