A New Predictive Index for Osteoporosis in Men under 70 Years of Age: An Index to Identify Male Candidates for Osteoporosis Screening by Bone Mineral Density

Table 4

Area under the ROC curve, sensitivity, specificity, and the optimal cut-off value (only of predictive index) of variables to predict osteoporosis in men under 70 years of age.

	AUC (95% CI)	𝑃 value^‡	Sensitivity (%)	Specificity (%)	Cut-off value
Weight	0.69 (0.60–0.77)	0.001	75.0	57.8	70.5
BMI	0.66 (0.56–0.77)	0.002	50.0	69.4	24.0
OST*	0.69 (0.61–0.78)	<0.001	78.1	58.4	2.5
PIO^†	0.74 (0.66–0.81)	<0.001	71.9	70.0	0.87

ROC: receiver operating characteristics; AUC: area under the curve; CI: confidence interval; BMI: body mass index.
∗Osteoporosis self-assessment tool [weight (kg) – age (years)]  × 0.2, decimal dropped.
†Predictive index for osteoporosis [age (years) + 10 (for current smoker)]/weight (kg)].
‡Null hypothesis: true area = 0.5.