Research Article

Association of MRS-Based Vertebral Bone Marrow Fat Fraction with Bone Strength in a Human In Vitro Model

Table 1

Mean and SD values of experimental parameters measured with MRS (proton density fat fraction), biomechanical testing (failure load and normalized failure load), and MDCT (mean transverse cross-sectional area, BMD, and trabecular microstructure parameters).

Fat fraction (%)32 ± 5
Mean transverse area (cm2)6.5 ± 1.5
Norm. failure load (N/cm2)442 ± 251
Failure load (N)2580 ± 1093
BMD (mg/cm3)121.5 ± 34.3
BV/TV (%)38.8 ± 10.8
TbN (mm−1)1.13 ± 0.11
FD1.57 ± 0.07