Clinical Study

The Effect of Long-Term Exercise on the Production of Osteoclastogenic and Antiosteoclastogenic Cytokines by Peripheral Blood Mononuclear Cells and on Serum Markers of Bone Metabolism

Figure 8

Estradiol and the antiresorptive effect of exercise. Postexercise CTXI levels correlate inversely with estradiol levels (Pearson correlation test with regression analysis). The results suggest that estradiol enhanced the antiresorptive effects of the exercise training program. Note: the correlation improves with removal of the apparent outlier (425 pg/mL estrogen): and .