Journal of Osteoporosis / 2016 / Article / Tab 3

Research Article

The Effects of Noncompliance to Prolia (Denosumab) on the Changes in Bone Mineral Density: A Retrospective Review

Table 3

Regression analysis comparing change in bone mineral density (BMD) between groups [reference group: 5–7 months].

Groups: time between 1st and 2nd injection wasEstimate95% confidence limits

Lumbar spineGreater than 7 months0.00035−0.0124 to 0.0131
Less than 5 months0.020−0.0058 to 0.0479

Femoral neckGreater than 7 months−0.0054−0.0171 to 0.0063
Less than 5 months0.0079−0.0165 to 0.0324

All multivariable regression analyses were adjusted for baseline BMD values, age of the patient, proton pump inhibitors (yes/no), selective serotonin reuptake inhibitors (yes/no), serotonin-norepinephrine reuptake inhibitors (yes/no), tricyclic antidepressants (yes/no), and the number of months between the first and second BMD measurements.

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