Journal of Osteoporosis / 2016 / Article / Tab 3

Research Article

Effect of Denosumab on Bone Mineral Density and Markers of Bone Turnover among Postmenopausal Women with Osteoporosis

Table 3

BMD in patients treated with Dmab (BP-naïve and BP-prior) and BP treated patients not switched to Dmab (control group).

Basal12 mChange (%)

BP-naïve
LS BMD (g/cm2)0.866 ± 0.0170.912 ± 0.018#↑5.31
FN (g/cm2)0.780 ± 0.0170.811 ± 0.018#↑3.97
TH (g/cm2)0.749 ± 0.0150.772 ± 0.014#↑3.07

BP-prior
LS BMD (g/cm2)0.861 ± 0.0080.908 ± 0.008↑5.46
FN (g/cm2)0.735 ± 0.0080.766 ± 0.009↑4.22
TH (g/cm2)0.736 ± 0.0060.757 ± 0.007↑2.85

Control group
LS BMD (g/cm2)0.906 ± 0.0090.923 ± 0.010θ↑1.88%
FN (g/cm2)0.745 ± 0.0090.752 ± 0.008ns
TH (g/cm2)0.756 ± 0.0120.758 ± 0.013ns

Significant differences with BP-naïve basal; significant differences with BP-prior basal; significant differences with control group basal.

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