Review Article
A Review on the Relationship between Aspirin and Bone Health
Table 2
The association between aspirin use and bone mineral density and fracture risk.
| Authors (years) | Characteristics of the subjects | Study design | Findings | Bone mineral density (BMD) | Fracture risk |
| Bauer et al. 1996 [30] | 7,786 Caucasian women aged 65 years above from the multicentred Study of Osteoporotic Fractures. | BMD measured cross-sectionally and fractures were followed up after 4 years. | ↑ | ↔ | Carbone et al. 2003 [32] | 2,853 subjects (49.5% women, 50.5% men) aged 73.6 years from the Health, Aging, and Body Composition Study. | BMD measured by DXA and QCT cross-sectionally. | ↑ | NA | Vestergaard et al. 2012 [31] | 2,016 female participants aged 45–58 years from the Danish Osteoporosis Prevention Study. | BMD and fracture of the participant were traced for 10 years. | ↔ | ↔ | Vestergaard et al. 2012 [33] | Cases = 124,655 subjects aged 43.44 (SD = 27.39) years. Control = 373,962 subjects aged 43.44 (SD = 27.39) years. | Case-control study | NA | ↑ |
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