Research Article
The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24−/− Progeria Mouse Model
Figure 4
Fisetin reduces senescence-associated transcripts. (a) Weekly dosing strategy for FIS treatments. (b) qPCR data for senescence marker p16INK4A and proinflammatory SASP factors IL-6 and TGF-β. Quantification based on ΔΔCt method for relative gene expression (n = 3, ).
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