Research Article

Changes in Testing and Treatment Methods in Osteoporosis Care

Table 3

Postmatching test items, prescription details, and knowledge acquisition methods.

20152020 value

The number of doctors extracted7474

Examination ItemsXp of the thoracolumbar spine (%)45 (60.8)38 (51.4)0.25
Bone mineral density of the lumbar spine and hip joint (%)30 (40.5)47 (63.5)
MRI of spine (%)4 (5.4)2 (2.7)0.40
No further examination (%)15 (20.3)8 (10.8)0.11

Breakdown of bone metabolic markersAny bone metabolic markers (%)59 (79.7)60 (81.1)0.84
Urinary NTX (%)22 (29.7)9 (12.2)
Serum NTX (%)4 (5.4)12 (16.2)
BAP (%)12 (16.2)11 (14.9)0.82
P1NP (%)23 (31.1)44 (59.5)
TRACP-5b (%)33 (44.6)52 (70.3)
ucOC (%)1 (1.4)3 (4.1)0.31
DPD (%)0 (0)0 (0)1.00

Blood test25(OH)D2 (2.7)19 (26.7)p<0.001

TreatmentActive vitamin D3 (%)50 (67.6)59 (79.7)0.09
SERM (%)16 (21.6)18 (24.3)0.70
Bisphosphonate (%)54 (73.0)39 (52.7)0.11
Denosumab (%)5 (6.8)6 (8.1)0.75
PTH preparation (%)9 (12.2)17 (23.0)0.08
Romosozumab (%)0 (0)3 (4.1)0.08
Vit K2 (2.7)0 (0)0.15

Exercise therapyExercise therapy (%)37 (50.0)41 (55.4)0.51

Nutritional guidanceNutritional guidance (%)26 (35.1)32 (43.2)0.31

KnowledgeTreatment experience (%)43 (58.1)40 (54.1)0.62
Guidelines (%)25 (33.8)24 (32.4)0.86
Lectures (%)16 (21.6)19 (26.7)0.56
Textbooks (%)6 (8.1)5 (6.8)0.75
Colleagues (%)2 (2.7)1 (1.4)0.56
Medical representative (%)2 (2.7)1 (1.4)0.56
No response (%)0 (0)2 (2.7)0.15

Statistical analysis included a Chi-square test. Xp: X-ray photography; MRI: magnetic resonance imaging, NTX: type I collagen cross-linked N-telopeptide; BAP: alkaline phosphatase; P1NP: procollagen I N-terminal propeptide; TRACP-5b: tartrate-resistant acid phosphatase 5b; PTH: parathyroid hormone; ucOC: undercarboxylated osteocalcin; DPD: deoxypyridinoline. Duplicate responses were obtained.