An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population

Table 3

The odds ratios (95% CI) for preeclampsia (PE). Severe PE and small-for-gestational age (SGA) associated with maternal FTO SNP rs9939609 AA and AT genotypes as well as with each additional A allele (unadjusted and adjusted) in a Finnish study population.

	OR (95% CI) for outcome
Covariates	PE	Severe PE**	SGA
TT	reference	reference	reference
AT*	1.30 (0.97.1.72)	1.31 (0.95.1.79)	1.05 (0.70.1.57)
AA*	1.12 (0.75.1.66)	0.98 (0.62.1.53)	0.83 (0.45.1.50)
Per A-allele, unadjusted*	1.10 (0.91.1.33)	1.05 (0.85.1.30)	0.94 (0.72.1.24)
Per A-allele, adjusted for log-transformed BMI*	1.09 (0.89.1.32)	1.04 (0.84.1.28)	0.91 (0.69.1.21)
Per A-allele, adjusted for log-transformed BMI, age and diabetes*	1.09 (0.90.1.32)	1.03 (0.83.1.28)	0.90 (0.68.1.20)

*Binary logistic regression analysis.
**Nonsevere PE cases excluded.