Differential Gene Expression Analysis of Placentas with Increased Vascular Resistance and Pre-Eclampsia Using Whole-Genome Microarrays
Table 1
Clinical characteristics of patients at delivery.
Control
PE
PE/N
Notch
N
15
10
5
5
Age (y)
31 (24–37)
29 (22–34)
32 (27–39)
32 (23–39)
Gestational age (days)
280 (253–295)
264 (227–285)
241 (204–283)
250 (219–284)
Systolic pressure (mmHg)
120 (110–135)
159 (140–170)
151 (145–160)
110 (115–120)
Diastolic pressure (mmHg)
75 (60–80)
105 (100–120)
100 (98–105)
78 (60–80)
Proteinuria (g/l)
0 (0–0.3)
3 (0.3–5)
3 (0.3–5)
0 (0-1)
Birth weight (g)a
3780 (2900–4315)
3100 (2500–3860)
1590 (1100–3430)
2790 (1400–3850)
Gender M : F
7 : 8
5 : 5
2 : 3
3 : 2
Pulsatility index
NA
0.69 (0.59–0.73)
0.99 (0.67–1.43)
0.93 (0.83–1.76)
Mode of delivery (VD : CS)
15 : 0
7 : 3
3 : 2
4 : 1
All data is presented as median (range) except child gender (Male : Female) and mode of delivery (VD : CS). A Kruskal-Wallis post hoc Dunn test was used to calculate statistical differences between the groups. PE: pre-eclampsia, PE/N: pre-eclampsia with bilateral notching, NA: not available, VD: vaginal delivery, and CS: caesarian section. aA significant difference between controls versus PE/N ().
