|
KEGG pathway analyses | KEGG ID | -value | FC |
|
Pathway |
PE compared to controls | | | |
āNeurodegenerative disorders | HSA01510 | .04 | 9.1 |
āāSOD1 and PSEN1 |
PE without notch compared to notch | | | |
āAntigen processing and presentation | HSA04612 | .04 | 3.1 |
āāHLA-B, HSP90AA1, PSME2, and CD74 |
PE with notch compared to notch | | | |
āUbiquitin mediated proteolysis | HSA04120 | .02 | 12.0 |
āāUBE2E2, TCEB2, and ANAPC2 |
Notch compared to controls | | | |
āLeukocyte transendothelial migration | HSA04670 | .03 | 5.7 |
āāACTG1, FKSG30, CXCR4, and CLDN5 |
āFocal adhesion | HSA04510 | .03 | 4.0 |
āāACTG1, FKSG30, FLT1, and CAV1 |
|
InterPro protein domain analyses | InterPro ID | -value | FC |
InterPro term |
|
PE compared to controls | | | |
āHEAT | IPR000357 | .05 | 4.5 |
āāTNPO1 and PPP2R1A |
āRas small GTPase, Rab type | IPR003579 | .05 | 3.6 |
āāRAB9B, RAB17, and RHOH |
PE compared to notch | | | |
āHEAT | IPR000357 | .003 | 4.3 |
āāARMC8, IPO13, PPP1R12B, and GCN1L1 |
āH+ transporting ATPase, proton pump | IPR000695 | .008 | 21.4 |
āāATP13A1 and ATP2A2 |
āHaloacid dehalogenase-like hydrolase | IPR005834 | .01 | 5.7 |
āāATP13A2, ATP13A1, and ATP2A2 |
PE with notch compared to notch | | | |
āATPase, F0/V0 complex | IPR002379 | .02 | 7.4 |
āāATP6V0C and ATP5G1 |
Notch compared to controls | | | |
āActin | IPR004001 | .04 | 44.1 |
āāACTG1 and FKSG30 |
|