Use of Medicines with Unknown Fetal Risk among Parturient Women from the 2004 Pelotas Birth Cohort (Brazil)
Table 4
Description of the sample and the health conditions of the mothers participating in the 2004 Birth Cohort (), prevalence (%) and adjusted analyses of the use of medicines during pregnancy considering all medicines and the medicines with unknown fetal risk used, excluding vitamin and iron supplements. Birth Cohort of Pelotas, RS 2004.
Use of medicines (total)
Use of medicines with unknow fetal risk
Characteristic
Adjusted analyses
Adjusted analyses
%
PR (IC 95%)
value
%
PR (IC 95%)
value
Total of participants
4,189
43.7
—
—
25.6
—
—
Age
0.275
0.883
<20
796
38.8
1.00
24.5
1.00
20 to 29
2,085
44.6
1.19 (0.98–1.44)
26.1
0.98 (0.78–1.23)
30 to 39
1,170
44.8
1.21 (0.98–1.50)
25.7
0.93 (0.70–1.23)
40 or more
136
47.8
1.25 (0.82–1.88)
23.5
0.85 (0.51–1.40)
Skin color
0.038
0.154
White
2,555
45.8
1.17 (1.01–1.35)
27.0
1.12 (0.96–1.32)
Non-white
1,586
40.2
1.00
23.1
1.00
Education in years
0.002
0.075
0 to 4
647
40.6
1.00
19.8
1.00
5 to 8
1,711
40.6
1.09 (0.88–1.35)
25.0
1.28 (1.02–1.61)
9 to 11
1,396
47.9
1.42 (1.12–1.79)
28.2
1.39 (1.08–1.78)
12 or more
435
46.9
1.56 (1.14–2.13)
28.5
1.36 (1.00–1.89)
Marital status
0.615
0.331
With the baby’s father
3,502
44.2
1.05 (0.86–1.29)
26.0
1.11 (0.90–1.39)
Without
687
41.0
1.00
23.3
1.00
Income per capita
0.009
0.020
1st quintile
830
39.0
1.00
20.5
1.00
2nd quintile
834
40.3
1.03 (0.83–1.28)
24.8
1.26 (1.00–1.59)
3rd quintile
886
45.8
1.37 (1.10–1.70)
24.8
1.21 (1.00–1.53)
4th quintile
849
46.5
1.37 (1.09–1.72)
28.5
1.45 (1.14–1.84)
5th quintile
790
46.6
1.30 (1.01–1.68)
29.5
1.48 (1.14–1.92)
Parity
0.991
0.830
primipara
1,658
43.5
0.99 (0.72–1.37)
26.5
0.94 (0.67–1.32)
1 or 2
1,086
44.5
1.01 (0.75–1.37)
25.9
0.91 (0.66–1.26)
3 or 4
1,026
44.4
0.98 (0.74–1.30)
24.5
0.88 (0.65–1.19)
5 or more
419
40.3
1.00
23.9
1.00
Prenatal consultation
0.747
0.277
<6
689
42.8
1.00
24.2
1.00
6 or more
3,250
43.9
0.96 (0.77–1.20)
26.2
0.88 (0.70–1.11)
Start of prenatal care
0.861
0.517
Before the 20th week
3,765
43.7
0.97 (0.71–1.33)
26.2
1.12 (0.80–1.58)
After the 20th week
283
40.6
1.00
20.8
1.00
Hospitalization
<0.001
<0.001
No
3,722
42.1
1.00
24.3
1.00
Yes
467
56.3
1.51 (1.20–1.89)
35.5
1.48 (1.19–1.84)
High Blood Pressure
<0.001
0.305
No
3,189
40.9
1.00
25.1
1.00
Yes
992
52.5
1.62 (1.38–1.90)
27.2
1.10 (0.92–1.31)
Diabetes
0.995
0.390
No
4,062
43.5
1.00
25.4
1.00
Yes
124
50.8
1.00 (0.67–1.50)
32.3
1.20 (0.79–1.81)
Depression
<0.001
0.066
No
3,138
41.5
1.00
24.8
1.00
Yes
1049
50.1
1.45 (1.24–1.70)
28.1
1.18 (0.99–1.40)
Anemia
<0.001
0.366
No
1,402
64.4
1.00
24.2
1.00
Yes
2756
32.9
0.23 (0.20–0.26)
26.4
1.08 (0.92–1.26)
Threat of abortion
0.003
<0.001
No
3,736
42.3
1.00
24.4
1.00
Yes
449
54.6
1.39 (1.11–1.73)
35.6
1.48 (1.19–1.83)
Threat of premature labor
<0.001
<0.001
Não
3,416
41.0
1.00
23.5
1.00
Sim
771
55.3
1.46 (1.22–1.76)
34.9
1.50 (1.25–1.80)
Urinary Infection
<0.001
0.434
Não
2,623
38.6
1.00
24.6
1.00
Sim
1,552
52.2
2.10 (1.81–2.42)
27.2
1.06 (0.91–1.24)
*Chi square test; **1st quintile relates to the most deprived quintile, ***PR: prevalence ratio.
