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Journal of Pregnancy
Volume 2012, Article ID 812094, 8 pages
http://dx.doi.org/10.1155/2012/812094
Research Article

Differential Effects of Chronic Pulsatile versus Chronic Constant Maternal Hyperglycemia on Fetal Pancreatic β-Cells

1Department of Pediatrics, Drexel University College of Medicine, Philadelphia, PA, USA
2Department of Animal Sciences, University of Arizona, Tucson, AZ 85719, USA
3Department of Pediatrics, UCD Perinatal Research Center, University of Colorado School of Medicine, 13243 East 23rd Avenue, MS F441, Aurora, CO 80045, USA

Received 6 August 2012; Accepted 2 October 2012

Academic Editor: Leena Hilakivi-Clarke

Copyright © 2012 Mackenzie S. Frost et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary materials include a table with maternal and fetal arterial blood gas and acid base data following the chronic experimental infusions. Also included in this table are the fetal blood gas and acid base data during the fetal hyperglycemic clamp. The supplementary materials also include a figure which shows time specific insulin and glucose concentrations during the fetal hyperglycemic clamp.

  1. Supplementary Materials