Research Article

Comparative Study of Endothelial Function and Uterine Artery Doppler Velocimetry between Pregnant Women with or without Preeclampsia Development

Table 1

Clinical characteristics and ultrasound parameters of pregnant women cohort, according to preeclampsia development.

Pregnant women without PE ( š‘› = 5 0 ) Preeclamptic women ( š‘› = 9 ) P value

Maternal age (years) 2 9 , 4 Ā± 6 , 5 2 9 , 4 Ā± 5 , 0 0,99**
Body mass index (kg/m2) 2 5 , 0 Ā± 6 , 6 2 7 , 5 Ā± 7 , 6 0,32**
Obese pregnant women7 (14%)2 (22%)0,24***
Number of gestations 2 (1ā€“8)2 (1ā€“5)0,27**
Primiparous16 (32.0%)3 (33.3%)0,17***
Ethnics: caucasian15 (30%)2 (22%)0,42***
Ethnics: Afro-American13 (26%)2 (22%)
Ethnics: other22 (44%)5 (56%)
Gestational age at enrolment (weeks) 1 7 , 6 Ā± 1 , 4 1 7 , 0 Ā± 1 , 3 0,24*
Mean arterial pressure at enrolment (mmā€‰Hg) 9 0 , 6 Ā± 7 , 8 9 2 , 2 Ā± 6 , 0 0,55*
Gestational age at second examination (weeks) 2 5 , 8 Ā± 1 , 2 2 5 , 6 Ā± 0 , 9 0,60*
Mean arterial pressure at second evaluation (mmā€‰Hg) 8 3 , 8 Ā± 7 , 3 4 8 8 , 1 Ā± 9 , 0 0,12*
Gestational age at delivery (weeks) 3 9 , 4 Ā± 0 , 9 3 5 , 0 Ā± 1 , 7 0,00*
UtA-PI at enrolment 1 , 0 7 Ā± 0 , 2 4 1 , 2 9 Ā± 0 , 1 5 0,01*
UtA-PI at second evaluation 0 , 8 3 Ā± 0 , 1 4 1 , 0 6 Ā± 0 , 1 4 <0,001*
UtA bilateral diastolic notch at second evaluation8 (16%)7 (78%)<0,001*
Basal diameter of brachial artery at enrolment (mm) 3 , 3 2 Ā± 0 , 4 7 3 , 3 4 Ā± 0 , 5 4 0,82*
Flow-mediated dilation between at enrolment (%) 5 , 5 8 Ā± 3 , 2 9 4 , 4 4 Ā± 3 , 6 1 0,35*
Basal diameter of brachial artery at second evaluation (mm) 3 , 3 6 Ā± 0 , 4 2 3 , 4 0 Ā± 0 , 4 9 0,81*
Flow-mediated dilation at second evaluation (%) 7 , 7 6 Ā± 2 , 8 9 4 , 2 2 Ā± 2 , 9 0 0,001*

Note: gestational age of enrolment: 16+0 to 19+6 weeks. Gestational age of second evaluation: 24+0 to 27+6 weeks . PE: preeclampsia, *Studentā€™s t-test, **Mann-Wthitney U test, ***Chi-square test.