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Journal of Pregnancy
Volume 2014 (2014), Article ID 239406, 13 pages
http://dx.doi.org/10.1155/2014/239406
Review Article

Gastroschisis: Antenatal Sonographic Predictors of Adverse Neonatal Outcome

Division of Maternal-Fetal Medicine, The Ottawa Hospital, General Campus, 501 Smyth Road, Room 8472, Ottawa, ON, Canada K1H 8L6

Received 28 August 2014; Accepted 27 November 2014; Published 22 December 2014

Academic Editor: R. L. Deter

Copyright © 2014 Rachael Page et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. The aim of this review was to identify clinically significant ultrasound predictors of adverse neonatal outcome in fetal gastroschisis. Methods. A quasi-systematic review was conducted in PubMed and Ovid using the key terms “gastroschisis,” “predictors,” “outcome,” and “ultrasound.” Results. A total of 18 papers were included. The most common sonographic predictors were intra-abdominal bowel dilatation (IABD), intrauterine growth restriction (IUGR), and bowel dilatation not otherwise specified (NOS). Three ultrasound markers were consistently found to be statistically insignificant with respect to predicting adverse outcome including abdominal circumference, stomach herniation and dilatation, and extra-abdominal bowel dilatation (EABD). Conclusions. Gastroschisis is associated with several comorbidities, yet there is much discrepancy in the literature regarding which specific ultrasound markers best predict adverse neonatal outcomes. Future research should include prospective trials with larger sample sizes and use well-defined and consistent definitions of the adverse outcomes investigated with consideration given to IABD.