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Journal of Pregnancy
Volume 2014, Article ID 431837, 6 pages
Research Article

Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country

1Department of Obstetrics and Gynaecology, Lady Hardinge Medical College and Associated Hospitals, New Delhi 110001, India
2Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
3Department of Biochemistry, Lady Hardinge Medical college and Associated Hospitals, New Delhi 110001, India

Received 13 November 2013; Revised 20 February 2014; Accepted 20 February 2014; Published 14 April 2014

Academic Editor: Sinuhe Hahn

Copyright © 2014 Archana Kumari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To investigate association between maternofoetal complications and the amount of proteinuria measured by spot urine protein creatinine ratio in patients with preeclampsia. Methods. 200 consecutive patients with preeclampsia were recruited in the study. The complications like first episode of severe hypertension, renal insufficiency, raised level of aspartate transaminase, signs of neurological involvement, thrombocytopenia, eclampsia, and need to shift in intensive care units were studied. The maternal outcome was studied in terms of type of labour, outcome of pregnancy, mode of delivery, indication of cesarean section, and maternal mortality. The foetal complications and outcome parameters were birth weight, Apgar score at the time of birth and at five minutes, need of high dependency unit care, and perinatal mortality. Result. The frequency of various maternal and foetal complications was between 14–53% and 22–92%, respectively. Maternal mortality was 3%, whereas perinatal mortality was 23%. Statistically significant association was found between the frequencies of various complications in mother and newborn and spot UPCR. Conclusion. The rate of various maternofoetal complications in preeclampsia is higher in developing countries than in developed world. Maternofoetal complications and outcome correlate with maternal spot UPCR.