Can Preterm Labour Be Predicted in Low Risk Pregnancies? Role of Clinical, Sonographic, and Biochemical Markers

Table 4

Showing sensitivity, specificity, and positive and negative likelihood ratios (LR) of some markers.

Marker	Biological sample	Sensitivity (%) (95% CI)	Specificity (%) (95% CI)	Positive LR	Negative LR
phIGFBP-1	Cervicovaginal fluid	2 (0.005–0.062)	97 (0.96–0.98)	90 (0.28–2.8)	100 (0.97–1.02)
ALP	Serum	14 (0.09–0.21)	99 (0.991–0998)	35.18 (15.21–81.41)	86 (0.80–0.91)
AFP	Serum	8 (0.04–0.14)	90 (0.84–0.94)	93 (0.45–1.92)	100 (0.95–1.05)
GCSF	Serum	12 (0.08–0.19)	99 (0.984–0.994)	13 (6.96–24.67)	88 (0.82–0.93)
IL6	Serum	8 (0.04–0.14)	99 (0.984–0.994)	8.96 (4.44–18.10)	92 (0.87–0.96)
Cervical length	—	14 (0.09–0.21)	98 (0.97–0.99)	9.85 (5.65–17.16)	80 (0.81–0.92)