Safety and Efficacy of Misoprostol versus Oxytocin for the Prevention of Postpartum Hemorrhage

Table 1

Comparison of study outcomes in the two groups.

Outcomes	Group 1 (𝑛=200)	Group 2 (𝑛=200)	𝑃 value
Amount of hemorrhage (gr)	182.4±101.3	157.0±84.9	0.007
Hb (mg/dL)	10.9±1.5	10.7±1.4	0.243
HCT (%)	32.2±4.2	32.7±3.6	0.200
Hb decrease (mg/dL)	0.8±1.1	0.7±0.9	0.363
HCT decrease (%)	2.2±3.3	2.1±2.7	0.629
Additional oxytocin	21 (10.5%)	9 (7.5%)	0.018
Any adverse effects	7 (3.5%)	30 (15%)	0.001
Transfusion	4 (2%)	1 (0.5%)	0.184
Hypotension*	1 (0.5%)	0 (0%)	0.5
Fever	4 (2%)	29 (14.5%)	𝑃<0.001
Chills	2 (1%)	2 (1%)	0.688

∗Defined as systolic BP≤90 mmHg or diastolic BP≤60 mmHg.