Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study

Table 2

Association between TSH (mU/L) and TPOAb (U/mL) levels and the number of children born, the number of pregnancies, and spontaneous abortion.

	Age-adjusted		Multiadjusted
	Coefficient (95% CI)	value	Coefficient (95% CI)	value
	Number of children born
	−0.046 (−0.068–(−0.023))	<0.001	−0.050 (−0.072–(−0.0272))	<0.001
	−0.020 (−0.037–(−0.003))	0.02	−0.021 (−0.038–(−0.004))	0.02
	Number of pregnancies
	−0.081 (−0.132–(−0.030))	0.002	−0.085 (−0.136–(−0.033))	0.001
	−0.019 (−0.055–0.017)	0.31	−0.021 (−0.058–0.016)	0.27
	Spontaneous abortion (yes versus no)
	0.96 (0.91–1.01)	0.12	0.95 (0.89–1.01)	0.08
	1.00 (0.95–1.04)	0.86	1.00 (0.96–1.04)	0.94

Multiadjusted model: age, menopause, BMI, smoking, diabetes, antihypertensive medication, cholesterol lowering medication, contraception, income, unemployment, and education.
Correlation between TSH and TPOAb and number of children born and number of pregnancies are measured was by linear regression.
Association between TSH and TPOAb and spontaneous abortion (yes vs. no) was by logistic regression.