AngiomiRs: Potential Biomarkers of Pregnancy’s Vascular Pathologies

Table 1

AngiomiRs detected in pregnancy’s vascular diseases.

Study	Pathology	Gestation age in which miRNAs were detected (weeks)	Tissue used
			Serum	Plasma	Placenta
[28]; [83]; [44]	PE	<20; 26–40; <20	miR-210 ↑; miR-144 ↓ (severe and mild PE); miR-29a ↑ (mild PE)	miR-210 ↑ (severe and mild PE); miR-210 ↑
[33, 51]		Perinatal			miR-16 ↑ (severe PE)
[55]		26			miR-125b-1-3p ↑
[31, 39]		39-40			miR-155 ↑ (severe PE)
[47]		36			miR-328 ↓
[32]		5–12; 13–25; 26–40			miR-378a-5p ↓
[38]		Perinatal			miR-29b ↑ (severe late onset PE)
[64]		Perinatal			miR-21 ↑ (early onset PE with IUGR)
[33]	IUGR	Perinatal			miR-16 ↑; miR-21 ↑
[69]		Perinatal			miR-424 ↑
[72]	Gestational diabetes	Second trimester	miR-29a ↓; miR-222 ↓; miR-132 ↓

↓ indicates decrease in miRNA expression.
↑ indicates increase in miRNA expression.