Research Article
Can Obstetric Risk Factors Predict Fetal Acidaemia at Birth? A Retrospective Case-Control Study
| | | Obstetric risk factors | Non-acidaemia
pH > 7.20 (N = 294) | Acidaemia
pH < 7.20 (N = 294) | Missing % | p-value | Odds ratios (95% CI) |
| | Past medical history | Pre-gestational diabetes (PGDM) | 2 (1.1%) | 10 (5.3%) | 39.3% | 0.018 | 5.31 (1.15 - 24.58) | | Thyroid disease | 10 (5.5%) | 15 (8.4%) | 38.4% | 0.274 | 1.58 (0.69 - 3.62) | | Rheumatological disease | 0 (0.0%) | 5 (2.8%) | 39.1% | 0.061 | 0.99 (0.97 - 0.99) | | Cardiac disease | 17 (9.2%) | 11 (6.1%) | 38.3% | 0.269 | 0.64 (0.29 - 1.76) | | Asthma | 40 (21.4%) | 41 (22.4%) | 37.1% | 0.814 | 1.06 (0.65 - 1.74) |
| | Past obstetric history | Caesarean section | 38 (20.1%) | 37 (19.8%) | 36.1% | 0.938 | 0.98 (0.59 - 1.63) | | Preterm | 8 (4.4%) | 8 (4.5%) | 38.9% | 0.936 | 1.04 (0.38 - 2.84) | | Stillbirth | 5 (2.8%) | 3 (1.7%) | 39.1% | 0.724 | 0.61 (0.14 - 2.58) | | Miscarriage | 57 (29.8%) | 50 (27.2%) | 36.2% | 0.567 | 0.88 (0.56 - 1.37) |
| | Prenatal risks | Smoking | 35 (13.9%) | 33 (11.6%) | 8.8% | 0.412 | 0.81 (0.49 - 1.35) | | Other recreational drugs | 12 (6.2%) | 19 (9.5%) | 33.0% | 0.233 | 1.58 (0.74 - 3.34) | | Anaemia | 50 (27.2%) | 52 (28.1%) | 37.2% | 0.841 | 1.05 (0.66 - 1.65) | | Urinary tract infection (UTI) | 12 (6.6%) | 34 (18.5%) | 37.76% | 0.001 | 3.21 (1.61 - 6.43) | | Pre-eclampsia | 35 (18.9%) | 50 (27.3%) | 37.80% | 0.056 | 1.61 (0.99 - 2.63) | | Antepartum haemorrhage (APH) | 16 (8.6%) | 11 (6.1%) | 37.93% | 0.370 | 0.70 (0.31 - 1.54) | | GDM (Gestational diabetes mellitus) | 14 (7.7%) | 11 (6.1%) | 38.27% | 0.563 | 0.79 (0.35 - 1.78) | | Obstetric cholestasis | 5 (2.8%) | 8 (4.5%) | 38.95% | 0.380 | 1.66 (0.53 - 5.16) | | IUGR (Intrauterine growth restriction) | 19 (10.3%) | 7 (4.0%) | 38.6% | 0.629 | 0.36 (0.15 - 0.87) | | RFM (Reduced Foetal Movement) | 42 (22.6%) | 56 (29.8%) | 36.4% | 0.113 | 1.46 (0.91 - 2.32) |
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Obstetric risk factors for acidaemia where the cutoff for acidaemia is pH = 7.20. Binary logistic regression was performed for all variables.
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