Journal of Pregnancy

Clinical Study

Magnesium Supplementation and Blood Pressure in Pregnancy: A Double-Blind Randomized Multicenter Study

Table 2

(a) Primary outcome. Increase from gestational week 12 to labour in diastolic (DBP) and systolic (SBP) blood pressure


Variable	Magnesium ( = 83)	Placebo ( = 93)	value

Increase in DBP ≥15 or SBP ≥30 mm Hg

0 (no)	46 (56.1%)	56 (60.2%)

1 (yes)	36 (43.9%)	37 (39.8%)	0.69

Increase in DBP of ≥15 mm Hg (maximum increase)

0 (no)	47 (57.3%)	57 (61.3%)

1 (yes)	35 (42.7%)	36 (38.7%)	0.70

Maximum increase in DBP	12.4 (8.3)	10.6 (9.4)	0.17
	10.0 (-5.0; 35.0)	10.0 (-10.0; 30.0)
	= 83	= 93

Increase in SBP of ≥30 mm Hg (maximum increase)

0 (no)	77 (93.9%)	84 (90.3%)

1 (yes)	5 (6.1%)	9 (9.7%)	0.56

Maximum increase in SBP	12.6 (10.7)	12.9 (11.7)	0.96
	10.0 (-10.0; 55.0)	10.0 (-5.0; 60.0)
	= 83	= 93

Gestational HT

0 (no)	62 (75.6%)	78 (83.9%)

1 (yes)	20 (24.4%)	15 (16.1%)	0.24

For categorical variables, (%) is presented.
For continuous variables, mean (SD)/median (min; max)/ is presented.
For comparison between groups, Fisher’s exact test (lowest 1-sided value multiplied by 2) was used for dichotomous variables and the Mann–Whitney test was used for continuous variables.

(b) Primary outcome. Increase from gestational week 12 to labour in diastolic blood pressure (DBP) and systolic blood pressure (SBP). Women taking extra Mg were excluded


Variable	Magnesium ( = 53)	Placebo ( = 58)	value

Increase in DBP ≥15 or SBP ≥30 mm Hg

0	27 (50.9%)	32 (55.2%)

1	26 (49.1%)	26 (44.8%)	0.80

Increase in DBP of ≥15 mm Hg (maximum increase)

0	28 (52.8%)	33 (56.9%)

1	25 (47.2%)	25 (43.1%)	0.81

Maximum increase in DBP	12.8 (8.0)	11.6 (8.4)	0.34
	10.0 (-5.0; 30.0)	10.0 (0.0; 30.0)
	= 53	= 58

Increase in SBP of ≥30 mm Hg (maximum increase)

0	50 (94.3%)	52 (89.7%)

1	3 (5.7%)	6 (10.3%)	0.58

Maximum increase in SBP	12.5 (9.0)	12.4 (11.2)	0.70
	10.0 (0.0; 35.0)	10.0 (-5.0; 50.0)
	= 53	= 58

Gestational HT

0	42 (79.2%)	48 (82.8%)

1	11 (20.8%)	10 (17.2%)	0.82