Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study

Figure 4

Gestational hypertension vs. preeclampsia. (a) Partial least squares-discriminant analysis (PLS-DA). This supervised discriminatory analysis shows preeclampsia (PE) in orange triangles and gestational hypertension (gHTN) in blue circles. (b) Venn diagram showing 169 overlapping significant features between linear regression ( value < 0.05) and PLS-DA (). (c) Box and whisker plots for 4 significant verified features (from left to right) SN-glycero-3-phosphocholine ( 258.1094; RT 76 s), retinoate ( 301.2174; RT 28 s), L-kynurenine ( 209.0922; RT 40 s), and 24-dihydroxyacetophenone ( 153.0577; RT 42 s).

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