Research Article

Maternal Serum Concentrations of Selenium, Copper, and Zinc during Pregnancy Are Associated with Risk of Spontaneous Preterm Birth: A Case-Control Study from Malawi

Table 1

Characteristics of study participants for term versus preterm births.

VariableCharacteristicTotal
Term births
Preterm births
value

Maternal age (years)Mean (SD)25.2 (6.1)26.32 (5.92)24.01 (6.19)0.011
Gestation (weeks)Mean (SD)35.6 (1.8)38.00 (1.04)33.36 (2.55)<0.0001
Birth weight (kg)Mean (SD)2.6 (0.4)3.14 (0.38)2.12 (0.48)<0.0001
Married/cohabitating (%)173 (96)87 (96.7)86 (94.5)0.766
Gravidity (%)0.048
 (i) 1-2108 (60)46 (51.1)62 (68.1)
 (ii) 3-561 (34)38 (42.2)23 (25.3)
 (iii) ≥612 (6.6)6 (6.7)6 (6.6)
Preterm baby before (%)16 (9)4 (4.4)12 (13.2)0.38
Education level (%)0.31
 (i) ≥college11 (6.1)5 (5.6)6 (6.6)
 (ii) secondary70 (38.7)41 (45.6)29 (31.9)
 (iii) primary91 (50.3)40 (44.4)51 (56.0)
 (iv) none9 (5)4 (4.4)5 (5.5)
Herbal medication use (%)32 (17.7)10 (11.1)22 (24.2)0.035
HIV positive (%)27 (15)14 (15.6)13 (14.3)0.975
Syphilis positive (%)1 (0.6)0 (0.0)1 (1.1)0.018

SD: standard deviation; : number; kg: kilograms. -test used for continuous variables, chi-square or Fisher’s exact test used for categorical variables.