Histological Changes Observed in Placentas Exposed to Medication-Assisted Treatment

Table 2

Placental findings in pregnant women using medication-assisted treatment (MAT) for control of opioid use disorder compared with healthy gestational age-matched control.

	Buprenorphine	Methadone	MAT	Controls
Placental dysmaturity	14 (34)	23 (35)	37 (36)	4 (10)
Placenta weight (grams)
grams	3 (7.3)	4 (6.2)	7 (6.8)	1 (2.5)
Fetoplacental weight ratio

Categorical data presented as (%) and continuous data presented as the . MAT: medication-assisted treatment. MAT groups compared to controls. ^‡ buprenorphine group compared to methadone group.