Review Article

Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis

Table 3

Data on 136 cases of maternal death due to COVID-19, details of which were available.

CaseStudy (country)Maternal age (years), gravida, para, gestational age (weeks)ComorbiditiesPresenting symptomsMode of deliveryDuration from admission to deathPolymerase chain reaction testing of the neonate
Advanced maternal ageObesityDiabetesAsthmaCardiovascularOther

1Ahmed, I. (United Kingdom)29, G2P1, 29NoYesYesYesNoRenal disease, vitamin D deficiencyFeverCesarean15 days from the first admission, 7 days from the second admissionNegative
2Karamim, P. (Iran)27, G2P1, 30NoNoNoNoNoNoFever, cough, myalgiaVaginal delivery3 daysN/A (stillbirth)
3Shojaei, S. (Iran)38, G2, Ab1, 23 (twin)YesNoNoNoNoNoFever, cough, dyspneaVaginal delivery17 daysN/A (death of both fetuses)
4Vallejo, V. (United States)36, G5P3Ab1, 37YesYesNoNoNoNoFever, cough, sore throatCesarean2 daysNegative
5Zamaniyan, M. (United States)22, not reported, 32 wNoNoNoNoNoHypothyroidismFever, cough, dyspnea, myalgia, anorexia, nauseaCesarean19 daysFirst negative, second test positive 24 hours later
6Hantoushzadeh, S. (Iran)25-29a, G2P1, 30NoNoNoNoNoNoFever, cough, dyspnea, myalgiaVaginal delivery4 daysN/A (fetal death)
725-29a, G1P0, 38NoYesNoNoNoNoFever, cough, dyspnea, myalgiaCesarean5 daysNegative
840-44a, G2P1, 30YesNoNoNoNoHypothyroidismFever, coughCesarean6 daysNegative on day of life 1, positive on day of life 7
930-34a, G3P0, 24NoNoNoNoNoNoFever, cough, dyspnea, myalgiaUndelivered8 daysN/A (fetal death)
1030-34a, G2P1, 36NoNoYesNoNoNoFever, coughCesarean10 daysNegative
1135-39a, G2P0, 24YesNoNoNoNoNoFever, cough, dyspnea, myalgiaUndelivered22 daysN/A (fetal death)
1245-49a, G2P1, 28YesNoNoNoNoUnderweightFever, cough, dyspneaCesarean18 daysNegative
13 to 136Takemoto, M.L.S. (Brazil)b31.5 (mean), no data about gravida or gestational age was availableNot reported13c22d5e13fNot reportedNot reportedNot reportedNot reportedNot reported

aMaternal age was gated in inclusive 5-year blocks (patient identification). b74 were pregnant and 50 were postpartum women. cMissing/unknown . dMissing/unknown . eMissing/unknown . fMissing/unknown .