Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening

Table 2

Differences between first trimester screening parameters according to the algorithm with a cut-off point for a PE risk >1 : 70 (n: number of patients; CRL: crown rump length; GA: gestational age (weeks); IQR: interquartile range).

Cut-off >1 : 70
Type of algorithm	(1) History+MAP+UtPI+PlGF	(2) History+MAP+UtPI+PlGF+PAPP-A	(3) History+MAP+UtPI+PAPP-A	(4) History+MAP+UtPI	value
Screen positive rate (%)	44/801 (5.5)	47/801 (5.9)	51/801 (6.4)	48/801 (6)
Age median (IQR)	35 (28.5-37)	35 (28-37)	35 (28-37)	44.5 (27.5-37)	0.96
Weight median (IQR)	73.25 (63-90)	72 (63-89)	72 (62.5-89)	74.75 (63.5-89)	0.97
Height median (IQR)	164 (160-169)	164 (160-170)	165 (160-170)	164.5 (160.5-170)	0.98
Parity median (IQR)	1 (0-1.5)	1 (0-1)	1 (0-2)	1 (0-2)	0.97
CRL(GA) median (IQR)	12.86 (12.43-13)	12.86 (12.43-13)	12.71 (12.29-13)	12.86 (12.57-13)	0.88
MoM UtPI median (IQR)	1.41 (1.12-1.58)	1.39 (1.12-1.58)	1.39 (1.12-1.58)	1.42 (1.13-1.59)	0.95
MoM PAPP-A median (IQR)	0.98 (0.7-1.27)	0.98 (0.69-1.29)	0.89 (0.68-1.26)	0.98 (0.7-1.26)	0.9
MoM PlGF median (IQR)	0.96 (0.8-1.19)	0.93 (0.74-1.17)	0.93 (0.76-1.2)	0.97 (0.8-1.19)	0.97
MoM MAP median (IQR)	1.23 (1.14-1.28)	1.22 (1.11-1.28)	1.22 (1.11-1.26)	1.17 (1.11-1.26)	0.49