Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening

Table 3

Differences between first trimester screening parameters according to the algorithm used with a cut-off point for a PE risk >1 : 100 (n: number of patients; CRL: crown rump length; GA: gestational age(weeks); IQR: interquartile range).

Cut-off >1 : 100
Type of algorithm	(1) History+MAP+UtPI+PlGF	(2) History+MAP+UtPI+PlGF+PAPP-A	(3) History+MAP+UtPI+PAPP-A	(4) History+MAP+UtPI	value
Screen positive rate (%)	58/801 (7.2)	60/801 (7.5)	59/801 (7.36)	61/801 (7.6)
Age median (IQR)	34.5 (28-37)	34.5 (28-36.5)	34 (28-36)	34 (28-36)	0.81
Weight median (IQR)	74.25 (63-89)	72 (62.75-89)	71 (61-89)	71.8 (62.5-89)	0.88
Height median (IQR)	164 (161-168)	164 (160.5-168)	165 (160-170)	165 (161-170)	0.81
Parity median (IQR)	1 (0-2)	1 (0-1.5)	1 (0-2)	1 (0-2)	0.96
CRL(GA) median (IQR)	12.86 (12.43-13)	12.86 (12.29-13)	12.71 (12.29-13)	12.86 (12.43-13)	0.92
MoM UtPI median (IQR)	1.34 (1.13-1.49)	1.32 (1.1-1.49)	1.36 (1.13-1.58)	1.39 (1.14-1.57)	0.93
MoM PAPP-A median (IQR)	0.98 (0.69-1.29)	0.95 (0.68-1.27)	0.95 (0.68-1.26)	0.94 (0.69-1.26)	0.98
MoM PlGF median (IQR)	0.97 (0.8-1.21)	0.93 (0.69-1.19)	0.95 (0.75-1.19)	0.97 (0.76-1.2)	0.87
MoM MAP median (IQR)	1.19 (1.09-1.26)	1.19 (1.1-1.27)	1.19 (1.11-1.26)	1.18 (1.11-1.25)	0.98