Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening

Table 4

Differences between first trimester screening parameters according to the algorithm used with a cut-off point for a PE risk >1 : 150 (n: number of patients; CRL: crown rump length; GA: gestational age(weeks); IQR: interquartile range).

Cut-off >1 : 150
Type of algorithm	(1) History+MAP+UtPI+PlGF	(2) History+MAP+UtPI+PlGF+PAPP-A	(3) History+MAP+UtPI+PAPP-A	(4) History+MAP+UtPI	value
Screen positive rate (%)	86/801 (10.7)	87/801 (10.9)	80/801 (10)	84/801 (10.5)
Age median (IQR)	33 (28-36)	33 (28-36)	32 (27.5-36)	33 (28-36)	0.9
Weight median (IQR)	71 (62.5-85)	70 (62-85)	69.1 (60.5-84)	70.5 (62.25-85.5)	0.96
Height median (IQR)	164 (160-168)	164 (160-168)	165 (160-170)	165 (160-170)	0.86
Parity median (IQR)	1 (0-2)	1 (0-1)	1 (0-1.5)	1 (0-1)	0.96
CRL(GA) median (IQR)	12.71 (12.29-13)	12.71 (12.29-13)	12.71 (12.29-13)	12.71 (12.29-13)	0.96
MoM UtPI median (IQR)	1.35 (1.13-1.55)	1.34 (1.13-.55)	1.35 (1.13-1.56)	1.34 (1.12-1.52)	0.97
MoM PAPP-A median (IQR)	0.96 (0.68-1.35)	0.98 (0.68-1.35)	0.96 (0.68-1.28)	0.94 (0.67-1.26)	0.89
MoM PlGF median (IQR)	0.93 (0.72-1.27)	0.94 (0.73-1.27)	0.93 (0.72-1.2)	0.92 (0.71-1.2)	0.92
MoM MAP median (IQR)	1.16 (1.08-1.25)	1.16 (1.09-1.25)	1.17 (1.11-1.25)	1.17 (1.11-1.25)	0.89