Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening
Table 6
Characteristics of the groups in terms of the cases detected compared to algorithm 1 (History+MAP+UtA-PI+PlGF) (n: number of patients; ASA: acetylsalicylic acid).
(1) History+MAP+UtPI+PlGF
(2) History+MAP+UtPI+PlGF+PAPP-A
(3) History+MAP+UtPI+PAPP-A
(4) History+MAP+UtPI
1 : 70 cut-off
Screen positive rate (%)
44 (5.5)
47 (5.9)
51 (6.4)
48 (6)
Cases found by both algorithm 1 and the tested algorithm (%)
44 (5.5)
41 (5.1)
38 (4.7)
Additional cases found for unnecessary ASA prophylaxis (%)
3 (0.37)
10 (1.2)
10 (1.2)
1 : 100 cut-off
Screen positive rate (%)
58 (7.2)
60 (7.5)
59 (7.36)
61 (7.6)
Cases found by both algorithm 1 and the tested algorithm (%)
56 (7)
42 (5.2)
41 (5.1)
Additional cases found for unnecessary ASA prophylaxis (%)
4 (0.5)
17 (2.1)
20 (2.5)
1 : 150 cut-off
Screen positive rate (%)
86 (10.7)
87 (10.9)
80 (10)
84 (10.5)
Cases found by both algorithm 1 and the tested algorithm (%)
83 (10.4)
62 (7.8)
60 (7.5)
Additional cases found for unnecessary ASA prophylaxis (%)
