Schizophrenia: A Pathogenetic Autoimmune Disease Caused by Viruses and Pathogens and Dependent on Genes

Table 3

Human proteins with homology to proteins expressed by pathogens. The size of the tags reflects the number of pathogen’s proteins that are homologous to the human protein: the filters used are described. The number of schizophrenia susceptibility genes within each of these datasets is shown in the left-hand column. Certain genes are classified according to family and are highlighted in red. Gene definitions and the original BLAST files can be found at http://www.polygenicpathways.co.uk/blasts.htm. Note that the homologues are often clustered in families (e.g., HTR1A, HTR2A, HTR3A, HTR3B, HTR3E, HTR5A, and HTR7).