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DISC1 partner gene symbol | Protein name | Viral binder |
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ACTG1 | Actin, cytoplasmic 2 | HIV-1 [97] HSV1 [98] |
ACTN2 | Actinin, alpha 2 | Hepatitis C [99] |
AKAP9 | A-kinase anchor protein 9 | Epstein-Barr [97] |
ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | HSV1 [98] |
ATF5 | Cyclic AMP-dependent transcription factor ATF-5 | HTLV1 [100] |
BICD1 | Protein bicaudal D homolog 1 | Cytomegalovirus [101] |
C14orf135 | Uncharacterized protein C14orf135 precursor | Hepatitis C [102] |
DCTN1 | Dynactin-1 | HSV1 [98] |
DCTN2 | Dynactin subunit 2 | Dynactins are involved in the transport of the adenoviruses, HSV-1, the hantaan virus, HTLV-1 and the poliovirus [103–108] |
DNAJC7 | DnaJ homolog subfamily C member 7 | Part of a complex forming the coxsackie virus receptor [109] |
DYNC1H1 | Dynein heavy chain, cytosolic | Adenovirus (in a complex with dynactin and NDEL1) [110] |
EEF2 | Elongation factor 2 | Epstein Barr [111] |
EIF3S3 | Eukaryotic translation initiation factor 3 subunit 3 | Hepatitis C [112] |
FEZ1 | Fasciculation and elongation protein zeta 1 (zygin I) | JC Polyomavirus [113] |
HERC2 | HECT domain and RCC1-like domain-containing protein 2 | Papillomavirus 16 [114] |
KIF3C | Kinesin-like protein KIF3C | HIV-1 [115] |
MATR3 | Matrin-3 | HSV1 [98] |
NDEL1 | Nuclear distribution protein nudE-like 1 | Part of a complex involved in Adenovirus transport (with dynactin and cytoplasmic dynein) [110] |
PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha | Binds to Poliovirus P3 protein and HIV-1 Tat [116, 117] |
PCNT | Pericentrin | Involved in the microtubular transport of the adenovirus [118] |
PGK1 | Phosphoglycerate kinase 1 | Epstein-Barr [119] |
SMARCE1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | HSV-1 [97] |
STX18 | Syntaxin-18 | Papillomavirus [119] |
TNKS | Tankyrase-1 | Epstein-Barr [120] |
TUBB | Tubulin beta chain | Epstein-Barr [119] |
YWHAE | 14-3-3 protein epsilon | Hepatitis C [97] : L : Epstein-Barr [119] |
YWHAQ | 14-3-3 protein theta | HIV [97] HSV1 [98] |
YWHAZ | 14-3-3 protein zeta/delta | HSV1 [98] : Epstein-Barr [119] |
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