Antifungal Susceptibility Patterns, In Vitro Production of Virulence Factors, and Evaluation of Diagnostic Modalities for the Speciation of Pathogenic Candida from Blood Stream Infections and Vulvovaginal Candidiasis
Table 1
Diagnostic accuracies of Vitek 2 Compact and HiCrome Agar in comparison with PCR.
Species ()* (Total = 105)
Vitek 2 Compact
HiCrome Agar
Sensitivity (%)
Specificity (%)
Sensitivity (%)
Specificity (%)
Confidence intervals (95%)
Confidence intervals (95%)
C. albicans (41)
93 (81–98)
100 (94–100)
100 (91–100)
91 (83–96)
C. tropicalis (30)
100 (88–100)
95 (88–98)
88 (72–96)
100 (95–100)
C. parapsilosis (18)
100 (82–100)
98.8 (94–99)
79 (72–100)
100 (96–100)
C. glabrata (13)
100 (75–100)
100 (96–100)
100 (76–100)
100 (92–99)
C. krusei (3)
100 (30–100)
100 (96–100)
100 (30–100)
100 (96–100)
Measure of agreement ()
0.895
0.826
Number of isolates identified using the species-specific PCR (reference method for speciation in our study).