Research Article

In Vivo Antimalarial Activity of Annona muricata Leaf Extract in Mice Infected with Plasmodium berghei

Table 2

Effect of A. muricata aqueous leaf extract on packed cell volume.

TreatmentDose (mg/kg)Packed cell volume
Day 0Day 4

A. muricata10053.24 ± 2.7340.14 ± 3.26
50050.56 ± 3.1248.22 ± 3.18
100053.71 ± 2.5952.15 ± 1.76

Chloroquine1051.55 ± 3.1452.47 ± 2.27

Distilled water1 mL52.15 ± 3.2538.26 ± 2.31

and , compared to day 0. Packed cell volume was expressed as mean ± SEM, . Chloroquine: positive control; distilled water: untreated control.