Investigations into Isoniazid Treated Mycobacterium tuberculosis by Electrospray Mass Spectrometry Reveals New Insights into Its Lipid Composition

Table 6

Comparison of number of lipids in each category identified from Mtb LipidDB and MycoMass databases in “control” and “INH-treated” samples. Number of observed m/z values interpreted and not interpreted by each of these two databases in “control” and “INH-treated” samples is also compared.

Sample: M. tb	Control (Untreated)		Common: Control		INH-Treated
			& INH-Treated
No. of observed m/z values	35		16		88
Databases	Mtb LipidDB∧	MycoMass	Mtb LipidDB∧	MycoMass	Mtb LipidDB∧	MycoMass
Lipid Categories
FA	5	6	2	3	11	16
GL	12	19	3	5	21	33
GPL	5	21	0	7	18	68
PK	0	16	0	1	2	30
PR	0	2	0	0	2	5
SL	0	5	0	0	0	6
Total No. of Lipids	22	69	5	16	54	158
No. of m/z values found in BOTH the databases	15		5		28
No. of m/z values found in; Mtb LipidDB ONLY	0		0		3
No. of m/z values found in MycoMass ONLY		10		4		33
No. of m/z values NOT found in both the databases	10		7		24

See Figure 6, wherein the data shown in this table have been depicted in the form of bar graph.