OmpA-Like Proteins of Porphyromonas gingivalis Mediate Resistance to the Antimicrobial Peptide LL-37

Figure 4

Sensitivity of the wild-type and Pgm6/Pgm7-deficient strains of P. gingivalis to the bactericidal activities of combinational treatment of hBD with LL-37. Bacterial cells (10⁷) of the wild-type and Pgm6/Pgm7-deficient strains, suspended in sTSB containing the indicated antimicrobial peptides (5 μM), were anaerobically cultured for 6 h. Bacterial survival was assessed by ATP production. Data are expressed as mean ± SD (n= 3). p < 0.05, one-way ANOVA and Dunnett’s test for post hoc comparisons (μc≠μi).