Research Article
Antimalarial Activity of Kaempferol and Its Combination with Chloroquine in Plasmodium berghei Infection in Mice
Table 1
Chronic oral toxicity of kaempferol in mice.
| Parameter | Control (10 ml/kg of DW) | 2,000 mg/kg of KMF |
| Liver function test | | | AST (U/L) | 39.07 ± 0.42 | 35.23 ± 0.72 | ALT (U/L) | 13.75 ± 0.32 | 13.25 ± 0.22 |
| Renal function test | | | BUN (mg/dl) | 45.55 ± 7.12 | 40.42 ± 2.34 | Creatinine (mg/dl) | 1.74 ± 0.31 | 1.57 ± 0.82 |
| Complete blood cells | | | Erythrocyte count (cells/mm3) | 6.13x106 ± 5.43 x 105 | 6.23x106 ± 5.23x105 | Leucocyte count (cell/mm3) | 1,618 ± 43.21 | 1,621 ± 25.67 | Neutrophils (%) | 35.45 ± 0.61 | 37.74 ± 0.85 | Eosinophils (%) | 2.14 ± 0.58 | 3.25 ± 0.45 | Basophils (%) | 4.10 ± 0.36 | 4.01 ± 0.55 | Monocytes (%) | 6.99 ± 0.35 | 6.56 ± 0.24 | Lymphocytes (%) | 56.00 ± 1.47 | 56.67 ± 2.47 |
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