Review Article

Prevalence of Multidrug-Resistant Tuberculosis and Associated Factors in Ethiopia: A Systematic Review

Table 2

Risk factors associated with MDR-TB in Ethiopia from 1994 to 2014.

Risk factorsNegative association with MDR-TBPositive association with MDR-TB

Previous exposure to anti-TB treatmentBiadglegne et al. [19]Agonafi et al. [12], Abate et al. [15], Abebe et al. [14], Nigus et al. [21], Mulisa et al. [24], Hamusse et al. [25], and Mekonnen et al. [26]
TB history of defaulterNRNigus et al. [21]
HIV/AIDSAbate et al. [15] and Abebe et al. [14]Yimer et al. [13], Tessema et al. [17], and Mulisa et al. [24]
AgeYimer et al. [13], Abate et al. [15], Biadglegne et al. [19], and Abebe et al. [14]Nigus et al. [21] and Mulu et al. [27]
Being maleYimer et al. [13], Abate et al. [15], and Abebe et al. [14]Biadglegne et al. [19], Mulisa et al. [24], and Abate et al. [16]
Occupation (farmer)NRMulisa et al. [24]
Known TB contact historyNRMulisa et al. [24]
Nonadherence to previous TB treatmentNRShegaw [22]
History of previous TB treatmentNRMulisa et al. [24], Shegaw [22], and Deressa and Demissie [28]
Opportunistic infectionNRDeressa and Demissie [28]
Newly treated casesAgonafir et al. [12], Abate et al. [15], and Abebe et al. [14]Mulu et al. [27]
Lack of formal educationNRMulisa et al. [24]
Low monthly incomeNRMulu et al. [27]
Cavitation on chest X-rayNRMulu et al. [27]
History of contact with MDR-TBNRMulu et al. [27]
Rural residenceNRMulisa et al. [24]
Alcohol useNRMulisa et al. [24] and Mulu et al. [27]
Chat chewNRMulisa et al. [24]
Previous unfavorable TB treatment outcomeNRMulisa et al. [24]
Previous history of TB treatment failureNRMulu et al. [27]
Primary educationNRDeressa and Demissie [28]
UnemploymentNRDeressa and Demissie [28]
Long distance to the healthcare facilityNRDeressa and Demissie [28]

NR: not reported.