Formulation and Characterization of Solid Dispersion Prepared by Hot Melt Mixing: A Fast Screening Approach for Polymer Selection

Figure 7

Solid state stability of different formulations described in Table 2 under accelerated conditions. The formulations evaluated were SUL (A), SUL + PPP + PEG1000 (B), SUL + PPP + TEC (C), SUL + HPC + PEG1000 (D), SUL + HPC + TEC (E), SUL + HPMC + PEG1000 (F), and SUL + HPMC + TEC (G). All the formulations were evaluated at 25°C/65% RH for 15 days, 40°C/75% RH for 15 days, 50°C for 3 days, and 100°C for 3 days.