Fast Disintegrating Combination Tablet of Taste Masked Levocetrizine Dihydrochloride and Montelukast Sodium: Formulation Design, Development, and Characterization

Table 1

Details of formulations (K1–K6) of batch formulation.

Batch-1
Levocetrizine dihydrochloride : Kyron-T-104 (1 : 4)
Ingredients	K1	K2	K3	K4	K5	K6
Montelukast sodium	10 mg	10 mg	10 mg	10 mg	10 mg	10 mg
MCC	176 mg	176 mg	176 mg	176 mg	176 mg	176 mg
SSG	4 mg	—	—	—	—	—
CCS	—	4 mg	—	—	—	—
CP	—	—	4 mg	—	—	—
SSG + CCS	—	—	—	4 mg	—	—
SSG + CP	—	—	—	—	4 mg	—
CCS + CP	—	—	—	—	—	4 mg
Mg stearate	2 mg	2 mg	2 mg	2 mg	2 mg	2 mg
Talc	3 mg	3 mg	3 mg	3 mg	3 mg	3 mg

MCC: microcrystlline cellulose; SSG: sodium starch glycolate; CCG: Crosscarmellose sodium; CP: crosspovidone.