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Journal of Pharmaceutics
Table of Contents
Journal of Pharmaceutics
/
2014
/
Article
/
Tab 11
/
Research Article
Fast Disintegrating Combination Tablet of Taste Masked Levocetrizine Dihydrochloride and Montelukast Sodium: Formulation Design, Development, and Characterization
Table 11
Postcompression evaluation of developed formulations.
Formulation
Postcompression evaluation parameters
Thickness (mm)
Diameter (mm)
Hardness (Kg/cm
2
)
Wt. variation
Friability
K1
3.12 ± 0.17
3.0 ± 0.38
3.1 ± 0.68
219.03 ± 1.08
0.49 ± 0.082
K2
3.13 ± 0.14
3.0 ± 0.27
3.2 ± 0.73
218.59 ± 0.94
0.52 ± 0.068
K3
3.12 ± 0.19
3.1 ± 0.28
3.4 ± 0.69
219.13 ± 1.11
0.57 ± 0.072
K4
3.11 ± 0.13
3.0 ± 0.24
3.2 ± 0.47
219.44 ± 0.92
0.47 ± 0.069
K5
3.13 ± 0.11
3.0 ± 0.33
3.3 ± 0.81
220.19 ± 0.91
0.53 ± 0.036
K6
3.12 ± 0.17
3.0 ± 0.36
3.0 ± 0.71
218.31 ± 0.89
0.37 ± 0.074