Journal of Parasitology Research / 2010 / Article / Tab 1

Research Article

Applicability of the Filter Paper Technique for Detection of Antifilarial I g G 4 Antibodies Using the Bm14 Filariasis CELISA

Table 1

Cross-tabulation results for the Filariasis CELISA comparing paired plasma and filter paper samples. The gold standard was considered to be the result derived from the plasma sample (columns). ELISA specifications for a filter paper eluate was found to be a sensitivity of 92% (95%-CI = 75–99), specificity of 77% (95%-CI = 65–86), positive predictive value (PPV) of 60% (95%-CI = 43–75), and negative predictive value (NPV) of 96% (95%-CI = 87–100).

Plasma

NegativePositiveTotal
Filter paperNegative52254
NPV96% (52/54)
Specificity77% (52/68)
Positive162440
PPV60% (24/40)
Sensitivity92% (24/26)
Total682694