Lagochilascaris minor: Susceptibility and Resistance to Experimental Infection in Mice Is Independent of H-2^a Haplotype and Correlates with the Immune Response in Immunized Animals

Figure 2

Lungs of mice infected with Lagochilascaris minor. Lungs of (a) an A/J mouse with perivascular and peribronchial mild inflammatory infiltration of macrophages and a few neutrophils (H&E, $\text{scale}=100\hspace{0.17em}\mu \text{m}$) and (b) a B10.A mouse (b) with severe and diffuse inflammatory infiltration composed of macrophages, neutrophils and few eosinophils (H&E, $\text{scale}=100\hspace{0.17em}\mu \text{m}$), both collected 30 days after infection. Lungs of (c) A/J mouse with varying degrees of damage, including secondary granuloma containing larvae in different degrees of destruction, concentric fibrosis and foci of inflammatory infiltration composed of macrophages (H&E, $\text{scale}=200\hspace{0.17em}\mu \text{m}$) and (d) B10.A mouse with secondary granuloma and severe and diffuse inflammatory infiltration in the lungs with a predominance of macrophages and few neutrophils (H&E, $\text{scale}=200\hspace{0.17em}\mu \text{m}$), both collected 60 days after infection.

(a)

(b)

(c)

(d)