Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes

Table 3

Effect of various concentrations of SPC liposomes containing 20 mol% SA on the hemolysis of infected & uninfected erythrocytes.

Concentration of liposomes (SA) μg/mL	% Hemolysis
	Infected RBC; (1% parasitemia)	Uninfected RBC
16.0	3.30 ± 0.34	0
8.0	1.91 ± 0.62	0
4.0	1.59 ± 0.85	0
2.0	0	0
1.0	0	0
0.5	0	0

SPC-SA liposomes at different concentrations were mixed with infected (1% parasitemia) and uninfected erythrocytes for 42 h as described in materials and methods. Percentage hemolysis was calculated using the expression % hemolysis = [A_405 nm (sample) − A_405 nm (negative control)]/A_405 nm (positive control).