Trypanosoma congolense Infections: Induced Nitric Oxide Inhibits Parasite Growth In Vivo
Figure 2
iNOS−/− mice infected with 103 T. congolense produce no detectable nitric oxide but more IL-10 than infected wild-type (WT) mice. Mice were infected with 103T. congolense. On day 6 postinfection, spleen cells were cultured at an optimal cell density (/mL) for 48 hours. Cytokines in culture supernatants were measured by ELISA, nitrite by the Griess reaction. *, **.