Trypanosoma congolense Infections: Induced Nitric Oxide Inhibits Parasite Growth In Vivo
Figure 3
iNOS−/− mice infected with T. congolense produce no detectable nitric oxide but more TNF-α, IL-10, and IFN-γ than infected wild-type (WT) mice. Mice were infected with T. congolense. On day 6 postinfection, spleen cells were cultured at an optimal cell density (/mL) for 48 hours. Cytokines in culture supernatants were measured by ELISA, nitrite by the Griess reaction. **.
