Journal of Parasitology Research / 2011 / Article / Tab 2

Clinical Study

Mebendazole Compared with Secnidazole in the Treatment of Adult Giardiasis: A Randomised, No-Inferiority, Open Clinical Trial

Table 2

Parasitological response and adverse events reported after treatment.

MBZSNZEstimated differences95% IC of difference
No.%No.%between MBZ-SNZ

Efficacy
Patients with parasitological cure *55/6485.956/6290.3−4.4%
**55/6288.756/6191.8−3.1%
Safety
Patients with at least one adverse event15/6423.420/6232.3−8.9%
Type of events adverse reported
Abdominal pain12 (18.7)14 (22.6)
Nausea5 (7.8) 4 (6.4)
Bitter taste2 (3.1) 15 (24.1)
Diarrhoea2 (3.1) 3 (4.8)
Dizziness0 (0) 6 (9.6)

*Intention-to-treat analysis for the no inferiority.
** Per-protocol analysis for the no inferiority.

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